Pr Jacques Marescaux IRCAD
Pr Rainer Haag, Berlin
Biomedical Applications of Dendritic and 2D Drug Delivery Systems
Rainer Haag, is Full Professor in Macromolecular Chemistry at the Freie Universität Berlin. Since 2021 he is the spokesperson of the Collaborative Research Center SFB 1449 « Dynamic Hydrogels at Biointerfaces « . His research interests are dendritic polymers as highly functional polymeric supports, macromolecular nanotransporters for drug-delivery and functional hydrogels at interfaces. Together with Dendropharm, he received the Berlin-Brandenburg Innovation Award 2016. Since 2019 he is an elected member of the German Academy of Science and Engineering (acatech). In 2022 he received and ERC Advanced Grant for his project SupraVir. His scientific output is documented by 590 peer review publications and 45 patent applications. For more information see the group homepage: www.polytree.de.
Dr Daniel JAQUE, Universidad Autónoma de Madrid (UAM), Spain
Luminescent nanothermometers for biomedical applicationsDaniel Jaque obtained his “Certificate in Physics” by the Sussex University (UK) in 1995, being incorporated at that time into Prof. Peter Townsend’s research group working on the optical properties of ion-implanted waveguides fabricated in nonlinear crystals. In 1996 he started his Ph.D thesis at the Universidad Autónoma de Madrid (UAM) within Prof. García-Sole´s group. In 1999 he successfully defended his Ph.D Thesis entitled “The NYAB: a red, green and blue solid state laser”. Then he moved to the Universidad Complutense de Madrid (UCM) as an assistant professor. As a member of Prof. J.L. Vicent´s group, he devoted two years to studying of the properties (optical and magnetic) of nano-structured magnetic thin films as well as to analysing vortex dynamics in nano-structured superconducting thin films. In 2001 he moved back to UAM and rejoined the Laser Spectroscopy group. During the following two years he was involved in the study of novel systems showing intrinsic optical bistability based either on ferroelectric transitions or in nonlinear pump induced heating processes. In 2006 he was awarded with the “Young Researcher Award” by the European Association for the Study of Rare Earths and Actanides. That same year he moved his research interest towards the micro/nano structuration of optical materials by ultrafast laser inscription covering not only practical aspects but also fundamental ones. Indeed, he has been a pioneer in the application of confocal fluorescence imaging techniques for the understanding of the light-matter interaction at the femtosecond time scale. The know-how acquired on confocal fluorescence imaging techniques has allowed him to face new research areas such as fluorescence imaging of living cancer cells and small animals for diagnosis and optically controlled treatments.
Thomas PONS, École Supérieure de Physique et de Chimie Industrielles (ESPCI), Paris, FRANCE
Zwitterionic polymer coatings for stable and stealthy nanocrystals in bioimaging and micromanipulation.
Thomas Pons obtained his PhD in 2004 from the Université Pierre et Marie Curie, Paris, in 2004, under the supervision of Jerome Mertz, on the applications of second harmonic generation to biological imaging. He then joined Hedi Mattoussi’s group at the Naval Research Lab, where he developed energy transfer fluorescent probes for biodetection using semiconductor quantum dots. In 2007, he joined the LPEM at ESPCI as a Chargé de Recherche INSERM. His research focuses on developing inorganic nanocrystals for biological applications. He synthesizes new inorganic nanomaterials, with controlled physical properties and surface functionalization, to design innovative tools for biodetection, imaging and therapy.
Florence Gazeau (Physicist, senior CNRS researcher, 52 years old, female) received her PhD in solid state physics from Université Paris Diderot in 1997. She is CNRS researcher since 1998 and senior researcher (DR1) since 2016. Since 2016, she is deputy director of Matière et Systèmes Complexes Lab, gathering more than 160 peoples at the interface of Physics, Biology, Chemistry and Environment. She created in 2019 the MSC Med antenna dedicated to medical translational research and bioengineering innovation on the Campus Saint Germain site, regrouping about 40 peoples from different disciplines, together with 2 spin-off companies and the expertise platform IVETh dedicated to extracellular vesicles biotherapies. She is author of 180 international publications in high impact factor interdisciplinary journal (ACS Nano, PNAS, Nanoletters, JACS, Biomaterials, Radiology, Advanced Materials, Advanced Functional Materials, ELife, Magnetic Resonance in Medicine …) with more than 15 000 citations and a factor h of 63 (https://scholar.google.com/citations?hl=fr&pli=1&user=shPWptkAAAAJ) ou (Orcid 0000-0002-6482-3597). She is co-inventor of 8 patent applications, 4 of which have been licensed to spin-off companies EVerZom and EVORA Bioscience, from which she is scientific adviser and co-founder, respectively. She gave more than 50 invited talks at conferences. Her work has established an internationally recognised research group in biomedical applications of nanoparticles (Cell tracking by MRI, Magnetic and photothermal therapy, tissue engineering), nanotoxicology, life cycle and long term fate of inorganic nanoparticles, nanometrology, mecanobiology of cancer and drug delivery and regenerative medecine with biological or bioinspired vesicles. She has been involved in 5 european projects (FP7,H2020 collaborative, Fet Open, MSCA Doctoral Network starting in 23) and more than 20 national projects.
C. Frochot was graduated from the Ecole Nationale Supérieure des Industries Chimiques (Nancy) and received her PhD degree in 1997 (LCPM, Nancy). She spent two years in Amsterdam, in the Van’t Hoff Institute for Molecular Science and became a CNRS researcher in 2000. Her interest is to develop novel photo-activable compounds for nanomedicine and PDT. She is the chairwoman of the Francophone Society of Medical Photonics (SFPMed), authors of 140 papers and 13 book chapters.
© Laurent Phialy
Prof. Mark Tibbitt has been Assistant Professor of Macromolecular Engineering at ETH Zurich since June 2017. Previously, he was an NIH Postdoctoral Fellow in the laboratory of Prof. Robert Langer in the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology. He received his B.A. in Integrated Science and Mathematics from Northwestern University, and his Ph.D. in Chemical Engineering at the University of Colorado Boulder under the supervision of Prof. Kristi S. Anseth. His research integrates concepts from chemical engineering, synthetic chemistry, materials science, and biology to rationally design and assemble soft matter for biomedical applications.
Prof. Maria J Vicent, Valencia, Spain
Designing Personalized Polymer-based Combination Nanomedicines for Advanced Stage Breast Cancer Patients
Dr. María J. Vicent received her Ph.D. degree in 2001 in chemistry after her research on solid supports from the Universitat Jaume I (Castellon, Spain) after several scientific stays in the laboratory of Prof. Fréchet’s lab. at the University California (Berkeley, USA). María then moved into more biomedically-oriented research, initially with the Spanish company Instituto Biomar S.A., and subsequently at the Centre for Polymer Therapeutics at the University of Cardiff (UK) with Prof. R. Duncan after receiving a Marie Curie Postdoctoral Fellowship in 2002. In 2004, María joined the Prince Felipe Research Center (CIPF, Valencia, Spain) as a research associate through a Marie Curie Reintegration contract and was promoted to her current position as the head of the Polymer Therapeutics Laboratory at CIPF in 2006. María is currently responsible for the Screening Platform one of the Specialist Sites in the EU-OPENSCREEN European Research Infrastructure Consortium (ERIC) and coordinates the Advanced Therapies Program at the CIPF. She is part of the Strategic Committee of the Valencian Agency of Innovation (AVI) and serves as Director at Large for the CRS since 2021.
Roy van der Meel is Assistant Professor of Precision Medicine at the Eindhoven University of Technology (TU/e). He conducted his Ph.D. research at Utrecht University under supervision of Wim Hennink and Gert Storm, focusing on developing nanomedicines to inhibit tumor growth and angiogenesis. After obtaining Marie Skłodowska-Curie funding and a Veni grant from the Dutch Research Council, Roy conducted postdoctoral research in the labs of Raymond Schiffelers at the University Medical Center Utrecht and Pieter Cullis at University of British Columbia. During his postdoctoral tenure, Roy gained extensive experience with developing lipid nanoparticle (LNP) technology that has enabled the first siRNA therapeutic and the COVID-19 mRNA vaccines. Since his recruitment to TU/e in 2019, Roy’s research is focused on establishing RNA platform nanotechnology to regulate the immune response in a highly precise manner.
Jessica Gobbo received her PhD in Life Sciences (Molecular and Cellular Biology and Oncology) from the University of Burgundy (Dijon, France) and her Master 2 in Business Administration (MBA, IAE, Dijon) in 2013. Since 2013, her research within the INSERM U1231 unit focuses on extracellular vesicles in cancer. In 2014, she joined the medical team of the early phase unit of the Georges-Francois Leclerc cancer center (Dijon). She coordinates different clinical trials on extracellular vesicles as biomarkers in cancer. She is co-founder of the East Extracellular Vesicle Network.
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